O-Antigen Delays Lipopolysaccharide Recognition and Impairs Antibacterial Host Defense in Murine Intestinal Epithelial Cells: e1000567

Although Toll-like receptor (TLR) 4 signals from the cell surface of myeloid cells, it is restricted to an intracellular compartment and requires ligand internalization in intestinal epithelial cells (IECs). Yet, the functional consequence of cell-type specific receptor localization and uptake-depen...

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Veröffentlicht in:	PLoS pathogens 2009-09, Vol.5 (9)
Hauptverfasser:	Duerr, Claudia U, Zenk, Sebastian F, Chassin, Cécilia, Pott, Johanna, Gütle, Dominique, Hensel, Michael, Hornef, Mathias W
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteria Bacterial infections Cell culture Ligands Microbiology Rodents Signal transduction
Online-Zugang:	Volltext
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