Cortical control of nociceptive transmission from the heart

Depriming effect of the cerebral cortex (predominantly of zones 1 and 2 of viscerosomatic sensitivity) on transmission of the cardiac afferent signals with a subcortical nociceptive component, which were provoked by electrical stimulation of the sinoatrial node of the heart conduction system, was es...

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Veröffentlicht in:Bulletin of experimental biology and medicine 1999-12, Vol.128 (6), p.1206-1208
Hauptverfasser: Churyukanov, V. V., Bilibin, D. P., Khodorovich, N. A., Shevelev, O. A.
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Sprache:eng
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Zusammenfassung:Depriming effect of the cerebral cortex (predominantly of zones 1 and 2 of viscerosomatic sensitivity) on transmission of the cardiac afferent signals with a subcortical nociceptive component, which were provoked by electrical stimulation of the sinoatrial node of the heart conduction system, was established in experiments on cats. The agonist of opiate M-receptors morphine considerably potentiated the effect of cortical stimulation, while opiate receptor blocker naloxone antagonized it.[PUBLICATION ABSTRACT]
ISSN:0007-4888
1573-8221
DOI:10.1007/BF02434818