A patient of chronic myelogenous leukemia developing painful rash on feet

Hand foot disease (HFD), also known as palmoplantar erythrodysaesthesia (PPE), is a distinctive cutaneous adverse drug reaction to certain chemotherapeutic agents. 5-Fluorouracil by infusion, capecitabine, cytarabine, docetaxel, and doxorubicin are the commonly implicated agents. [1] Here, we are re...

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Veröffentlicht in:Journal of postgraduate medicine 2012-10, Vol.58 (4), p.331-334
Hauptverfasser: Kumar, P, Das, N K, Sil, A, Chakrabarti, P
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container_title Journal of postgraduate medicine
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creator Kumar, P
Das, N K
Sil, A
Chakrabarti, P
description Hand foot disease (HFD), also known as palmoplantar erythrodysaesthesia (PPE), is a distinctive cutaneous adverse drug reaction to certain chemotherapeutic agents. 5-Fluorouracil by infusion, capecitabine, cytarabine, docetaxel, and doxorubicin are the commonly implicated agents. [1] Here, we are reporting a case of PPE in a patient receiving imatinib mesylate. PPE due to imatinib mesylate has been reported rarely; however, PPE due to other tyrosine kinase inhibitors are more common.
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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
subjects Adult
Antineoplastic Agents - adverse effects
Antineoplastic Agents - therapeutic use
Benzamides - adverse effects
Benzamides - therapeutic use
Case studies
Chronic myeloid leukemia
Complications and side effects
Development and progression
Diagnosis
Drug Eruptions - etiology
Drug Eruptions - pathology
Drug therapy
Exanthema - chemically induced
Exanthema - drug therapy
Foot diseases
Hand-Foot Syndrome
Humans
Imatinib Mesylate
Leukemia
Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy
Male
Palmar-plantar erythrodysesthesia
Piperazines - adverse effects
Piperazines - therapeutic use
Pyrimidines - adverse effects
Pyrimidines - therapeutic use
Side effects
Treatment Outcome
title A patient of chronic myelogenous leukemia developing painful rash on feet
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