A patient of chronic myelogenous leukemia developing painful rash on feet

Hand foot disease (HFD), also known as palmoplantar erythrodysaesthesia (PPE), is a distinctive cutaneous adverse drug reaction to certain chemotherapeutic agents. 5-Fluorouracil by infusion, capecitabine, cytarabine, docetaxel, and doxorubicin are the commonly implicated agents. [1] Here, we are re...

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Veröffentlicht in:	Journal of postgraduate medicine 2012-10, Vol.58 (4), p.331-334
Hauptverfasser:	Kumar, P, Das, N K, Sil, A, Chakrabarti, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antineoplastic Agents - adverse effects Antineoplastic Agents - therapeutic use Benzamides - adverse effects Benzamides - therapeutic use Case studies Chronic myeloid leukemia Complications and side effects Development and progression Diagnosis Drug Eruptions - etiology Drug Eruptions - pathology Drug therapy Exanthema - chemically induced Exanthema - drug therapy Foot diseases Hand-Foot Syndrome Humans Imatinib Mesylate Leukemia Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy Male Palmar-plantar erythrodysesthesia Piperazines - adverse effects Piperazines - therapeutic use Pyrimidines - adverse effects Pyrimidines - therapeutic use Side effects Treatment Outcome
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Zusammenfassung:	Hand foot disease (HFD), also known as palmoplantar erythrodysaesthesia (PPE), is a distinctive cutaneous adverse drug reaction to certain chemotherapeutic agents. 5-Fluorouracil by infusion, capecitabine, cytarabine, docetaxel, and doxorubicin are the commonly implicated agents. [1] Here, we are reporting a case of PPE in a patient receiving imatinib mesylate. PPE due to imatinib mesylate has been reported rarely; however, PPE due to other tyrosine kinase inhibitors are more common.
ISSN:	0022-3859 0972-2823
DOI:	10.4103/0022-3859.105489