Analysis of the peroxisome proliferator-activated receptor-[beta]/[delta] cistrome reveals novel co-regulatory role of ATF4

The present study coupled expression profiling with chromatin immunoprecipitation sequencing (ChIP-seq) to examine peroxisome proliferator-activated receptor-[beta]/[delta] (PPAR[beta]/[delta])-dependent regulation of gene expression in mouse keratinocytes, a cell type that expresses PPAR[beta]/[del...

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Veröffentlicht in:	BMC genomics 2012-11, Vol.13
Hauptverfasser:	Khozoie, Combiz, Borland, Michael G, Zhu, Bokai, Baek, Songjoon, John, Sam, Hager, Gordon L, Shah, Yatrik M, Gonzalez, Frank J, Peters, Jeffrey M
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding sites Cancer Cell receptors Chromatin DNA binding proteins DNA sequencing Gene expression Genes Genetic aspects Genetic transcription Genomes Hypothesis testing Ligands Medical research Nucleotide sequencing Physiological aspects Proteins RNA polymerase Rodents
Online-Zugang:	Volltext
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