Calcium oxalate crystals induce renal inflammation by NLRP3-mediated IL-1[Beta] secretion

Nephrocalcinosis, acute calcium oxalate (CaOx) nephropathy, and renal stone disease can lead to inflammation and subsequent renal failure, but the underlying pathological mechanisms remain elusive. Other crystallopathies, such as gout, atherosclerosis, and asbestosis, trigger inflammation and tissue...

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Veröffentlicht in:	The Journal of clinical investigation 2013-01, Vol.123 (1), p.236
Hauptverfasser:	Mulay, Shrikant R, Kulkarni, Onkar P, Rupanagudi, Khader V, Migliorini, Adriana, Darisipudi, Murthy N, Vilaysane, Akosua, Muruve, Daniel, Shi, Yan, Munro, Fay, Liapis, Helen, Anders, Hans-Joachim
Format:	Artikel
Sprache:	eng
Schlagworte:	Atherosclerosis Biomedical research Crystals Cytokines Inflammation Kidneys Potassium Rheumatism
Online-Zugang:	Volltext
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