Simultaneous Inhibition of COX-2 and Activation of PPAR-[gamma] Resulted in the Same Level and Pattern of Neuroprotection as They were Targeted Separately

The inflammatory response is an immune response of the body when exposed to internal and external stimuli. Cyclooxygenases (COX) are major inflammatory mediators implicated in inflammation. COX-2 is reported to be involved in neuroinflammation. Moreover, 15-Deoxy-d ^sup 12,14^-prostaglandin J2 (15d-...

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Veröffentlicht in:	Journal of molecular neuroscience 2013-01, Vol.49 (1), p.116
Hauptverfasser:	Abraki, Shahnaz Babaei, Khalaj, Leila, Shaerzadeh, Fatemeh, Khodagholi, Fariba
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants Apoptosis Cancer Enzymes Inflammation Ligands Neurodegeneration Nonsteroidal anti-inflammatory drugs Oxidative stress
Online-Zugang:	Volltext
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