Reprogramming of the MHC-I and Its Regulation by NF[kappa]B in Human-Induced Pluripotent Stem Cells

The immunogenicity of human pluripotent stem cells plays a major role in their potential use in the clinic. We show that, during their reprogramming, human-induced pluripotent stem (iPS) cells downregulate expression of human leukocyte antigen (HLA)-A/B/C and [beta]2 microglobulin ([beta]2M), the tw...

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Veröffentlicht in:	Stem cells (Dayton, Ohio) Ohio), 2012-12, Vol.30 (12), p.2700
Hauptverfasser:	Pick, Marjorie, Ronen, Daniel, Yanuka, Ofra, Benvenisty, Nissim
Format:	Artikel
Sprache:	eng
Schlagworte:	Medical research Stem cells
Online-Zugang:	Volltext
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