Hyaluronic Acid Derivative-Based Self-Assembled Nanoparticles for the Treatment of Melanoma

ABSTRACT Purpose Hyaluronic acid-ceramide (HACE)-based nanoparticles (NPs) were developed for the targeted delivery of doxorubicin (DOX), and their antitumor efficacy for melanoma was evaluated. Methods DOX-loaded HACE-based self-assembled NPs were prepared and their physicochemical properties were...

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Veröffentlicht in:Pharmaceutical research 2012-12, Vol.29 (12), p.3443-3454
Hauptverfasser: Jin, Yu-Jin, Termsarasab, Ubonvan, Ko, Seung-Hak, Shim, Jae-Seong, Chong, Saeho, Chung, Suk-Jae, Shim, Chang-Koo, Cho, Hyun-Jong, Kim, Dae-Duk
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Sprache:eng
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