Assessment of the novel tubulin-binding agent EHT 6706 in combination with ionizing radiation or chemotherapy

Summary The potential of EHT 6706, a novel tubulin-binding agent, was investigated in combination with ionizing radiation (IR) and with conventional cytotoxic chemotherapy agents. Cell proliferation, cell cycle, apoptosis and clonogenic assays were performed in five human cancer cell lines: H460 (no...

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Veröffentlicht in:Investigational new drugs 2012-12, Vol.30 (6), p.2173-2186
Hauptverfasser: Clémenson, Céline, Chargari, Cyrus, Désiré, Laurent, Casagrande, Anne-Sophie, Bourhis, Jean, Deutsch, Eric
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Sprache:eng
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