Role of alpha- and beta-calcitonin gene-related peptide in postoperative small bowel ileus

Ablation of α-calcitonin gene-related polypeptide (CGRP) containing neurons with the afferent neurotoxin capsaicin improves postoperative foregut transit in a rodent model. Similarly, administration of a selective α-CGRP antibody or hCGRP (8–37), a CGRP receptor antagonist, improves postoperative ga...

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Veröffentlicht in:	Journal of gastrointestinal surgery 1999-01, Vol.3 (1), p.39-43
Hauptverfasser:	Freeman, Mark E., Cheng, Guozhang, Hocking, Michael P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - immunology Antibodies, Monoclonal - pharmacology calcitonin Calcitonin Gene-Related Peptide - immunology Calcitonin Gene-Related Peptide - pharmacology Calcitonin Gene-Related Peptide - physiology Calcitonin Gene-Related Peptide Receptor Antagonists Disease Models, Animal Gastrointestinal Transit - drug effects Gastrointestinal Transit - physiology gene-related peptide ileus Intestinal Obstruction - etiology Intestinal Obstruction - physiopathology Intestine, Small - physiology Intestine, Small - surgery Male Peptide Fragments - pharmacology Peptides Postoperative Complications - etiology Postoperative Complications - physiopathology Random Allocation Rats Rats, Sprague-Dawley Rodents Small intestine
Online-Zugang:	Volltext
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