Possible Involvement of Transthyretin in Hippocampal [beta]-Amyloid Burden and Learning Behaviors in a Mouse Model of Alzheimer's Disease (TgCRND8)

Background: Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive memory loss, possibly triggered by the accumulation of β-amyloid (Aβ) peptides and the hyperphosphorylation of Tau neurofilament protein. Recent findings have shown that transthyretin (TTR) is a pot...

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Veröffentlicht in:Neuro-degenerative diseases 2010-04, Vol.7 (1-3), p.88
Hauptverfasser: Doggui, Sihem, Brouillette, Jonathan, Chabot, Jean-guy, Farso, Mark, Quirion, Rémi
Format: Artikel
Sprache:eng
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