The Central Kink Region of Fowlicidin-2, an [alpha]-Helical Host Defense Peptide, Is Critically Involved in Bacterial Killing and Endotoxin Neutralization

Fowlicidins are a group of newly identified chicken cathelicidin host defense peptides. We have shown that the putatively mature fowlicidin-2 of 31 amino acid residues possesses potent antibacterial and lipopolysaccharide (LPS)- neutralizing activities, but with a noticeable toxicity to mammalian ce...

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Veröffentlicht in:Journal of innate immunity 2009-04, Vol.1 (3), p.268
Hauptverfasser: Xiao, Yanjing, Herrera, Alvaro I, Bommineni, Yugendar R, Soulages, Jose L, Prakash, Om, Zhang, Guolong
Format: Artikel
Sprache:eng
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