Treatment of renal stones in infants: comparing extracorporeal shock wave lithotripsy and mini-percutaneous nephrolithotomy
The objective of the study is to compare the efficacy and safety of extracorporeal shock wave lithotripsy (ESWL) and mini-percutaneous nephrolithotomy (MPCNL) in treating renal stones sizing 15–25 mm in infants
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| Veröffentlicht in: | Urolithiasis 2012-10, Vol.40 (5), p.599-603 |
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| creator | Zeng, Guohua Jia, Jianye Zhao, Zhijian Wu, Wenqi Zhao, Zhigang Zhong, Wen |
| description | The objective of the study is to compare the efficacy and safety of extracorporeal shock wave lithotripsy (ESWL) and mini-percutaneous nephrolithotomy (MPCNL) in treating renal stones sizing 15–25 mm in infants |
| doi_str_mv | 10.1007/s00240-012-0478-y |
| format | Article |
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2
, Mann–Whitney
U
, and Student’s
t
tests. No significant differences in mean age and stone size were observed between the two groups. The 1- and 3-month postoperative stone-free rates were 84 and 96 % in MPCNL group and were 31.8 and 86.4 % in ESWL group. The re-treatment and complication rates were significantly higher in ESWL group than in MPCNL group (50 vs. 12 %,
P
= 0.004; 16.0 vs. 45.5 %,
P
= 0.028). The stone recurrence rate was similar between the two groups. No significant changes of serum creatinine (Cr) level and glomerular filtration rate were observed in both groups. In conclusion, MPCNL is an effective and feasible alternative monotherapy for large renal stones (15–25 mm) in infants, with a higher stone-free rate and a lower complication rate when compared with ESWL.</description><identifier>ISSN: 0300-5623</identifier><identifier>ISSN: 2194-7228</identifier><identifier>EISSN: 1434-0879</identifier><identifier>EISSN: 2194-7236</identifier><identifier>DOI: 10.1007/s00240-012-0478-y</identifier><identifier>PMID: 22580634</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject>Child, Preschool ; Female ; Humans ; Infant ; Infant, Newborn ; Kidney Calculi - therapy ; Lithotripsy - adverse effects ; Lithotripsy - methods ; Male ; Medical Biochemistry ; Medicine ; Medicine & Public Health ; Nephrology ; Nephrostomy, Percutaneous - adverse effects ; Nephrostomy, Percutaneous - methods ; Original Paper ; Urology</subject><ispartof>Urolithiasis, 2012-10, Vol.40 (5), p.599-603</ispartof><rights>Springer-Verlag 2012</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-44602a7e3faffc0b43e3c6bd4d9a7d1c067e3e450de29b62ca8cdfbd1f8e31ba3</citedby><cites>FETCH-LOGICAL-c372t-44602a7e3faffc0b43e3c6bd4d9a7d1c067e3e450de29b62ca8cdfbd1f8e31ba3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22580634$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zeng, Guohua</creatorcontrib><creatorcontrib>Jia, Jianye</creatorcontrib><creatorcontrib>Zhao, Zhijian</creatorcontrib><creatorcontrib>Wu, Wenqi</creatorcontrib><creatorcontrib>Zhao, Zhigang</creatorcontrib><creatorcontrib>Zhong, Wen</creatorcontrib><title>Treatment of renal stones in infants: comparing extracorporeal shock wave lithotripsy and mini-percutaneous nephrolithotomy</title><title>Urolithiasis</title><addtitle>Urol Res</addtitle><addtitle>Urol Res</addtitle><description>The objective of the study is to compare the efficacy and safety of extracorporeal shock wave lithotripsy (ESWL) and mini-percutaneous nephrolithotomy (MPCNL) in treating renal stones sizing 15–25 mm in infants <3 years. Forty-six infants with renal stones sizing 15–30 mm were treated by either ESWL (22 renal units in 22 infants) using Dornier compact delta lithotripter or MPCNL (25 renal units in 24 infants) using 14F–18F renal access under general anesthesia. The operation time, stone-free rate, re-treatment rate, and complications between the two groups were compared with the χ
2
, Mann–Whitney
U
, and Student’s
t
tests. No significant differences in mean age and stone size were observed between the two groups. The 1- and 3-month postoperative stone-free rates were 84 and 96 % in MPCNL group and were 31.8 and 86.4 % in ESWL group. The re-treatment and complication rates were significantly higher in ESWL group than in MPCNL group (50 vs. 12 %,
P
= 0.004; 16.0 vs. 45.5 %,
P
= 0.028). The stone recurrence rate was similar between the two groups. No significant changes of serum creatinine (Cr) level and glomerular filtration rate were observed in both groups. In conclusion, MPCNL is an effective and feasible alternative monotherapy for large renal stones (15–25 mm) in infants, with a higher stone-free rate and a lower complication rate when compared with ESWL.</description><subject>Child, Preschool</subject><subject>Female</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Kidney Calculi - therapy</subject><subject>Lithotripsy - adverse effects</subject><subject>Lithotripsy - methods</subject><subject>Male</subject><subject>Medical Biochemistry</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Nephrology</subject><subject>Nephrostomy, Percutaneous - adverse effects</subject><subject>Nephrostomy, Percutaneous - methods</subject><subject>Original Paper</subject><subject>Urology</subject><issn>0300-5623</issn><issn>2194-7228</issn><issn>1434-0879</issn><issn>2194-7236</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kU1rFTEUhoMo9rb6A9xIwE03qScf8-VOSrWFgpu6HjKZE-_UmWSaZNoO_nlzmSpFEAJZ5HnfHM5DyDsOZxyg-hgBhAIGXDBQVc3WF2THlVQM6qp5SXYgAVhRCnlEjmO8BeBV2YjX5EiIooZSqh35dRNQpwldot7SgE6PNCbvMNLB5WO1S_ETNX6adRjcD4qPKWjjw-xzMLN7b37SB32PdBzS3qcwzHGl2vV0GtzAZgxmSdqhXyJ1OO-D3zg_rW_IK6vHiG-f7hPy_cvFzfklu_729er88zUzshKJKVWC0BVKq6010CmJ0pRdr_pGVz03UOY3VAX0KJquFEbXprddz22NkndanpDTrXcO_m7BmNppiAbHcRur5SCbui6aosnoh3_QW7-EvJSNklIpcaD4RpngYwxo2zkMkw5rhtqDmXYz02Yz7cFMu-bM-6fmpZuw_5v4oyIDYgPifFg0hudf_6_1Nw3qnZk</recordid><startdate>20121001</startdate><enddate>20121001</enddate><creator>Zeng, Guohua</creator><creator>Jia, Jianye</creator><creator>Zhao, Zhijian</creator><creator>Wu, Wenqi</creator><creator>Zhao, Zhigang</creator><creator>Zhong, Wen</creator><general>Springer-Verlag</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20121001</creationdate><title>Treatment of renal stones in infants: comparing extracorporeal shock wave lithotripsy and mini-percutaneous nephrolithotomy</title><author>Zeng, Guohua ; Jia, Jianye ; Zhao, Zhijian ; Wu, Wenqi ; Zhao, Zhigang ; Zhong, Wen</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c372t-44602a7e3faffc0b43e3c6bd4d9a7d1c067e3e450de29b62ca8cdfbd1f8e31ba3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Child, Preschool</topic><topic>Female</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Kidney Calculi - therapy</topic><topic>Lithotripsy - adverse effects</topic><topic>Lithotripsy - methods</topic><topic>Male</topic><topic>Medical Biochemistry</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Nephrology</topic><topic>Nephrostomy, Percutaneous - adverse effects</topic><topic>Nephrostomy, Percutaneous - methods</topic><topic>Original Paper</topic><topic>Urology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zeng, Guohua</creatorcontrib><creatorcontrib>Jia, Jianye</creatorcontrib><creatorcontrib>Zhao, Zhijian</creatorcontrib><creatorcontrib>Wu, Wenqi</creatorcontrib><creatorcontrib>Zhao, Zhigang</creatorcontrib><creatorcontrib>Zhong, Wen</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Urolithiasis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zeng, Guohua</au><au>Jia, Jianye</au><au>Zhao, Zhijian</au><au>Wu, Wenqi</au><au>Zhao, Zhigang</au><au>Zhong, Wen</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Treatment of renal stones in infants: comparing extracorporeal shock wave lithotripsy and mini-percutaneous nephrolithotomy</atitle><jtitle>Urolithiasis</jtitle><stitle>Urol Res</stitle><addtitle>Urol Res</addtitle><date>2012-10-01</date><risdate>2012</risdate><volume>40</volume><issue>5</issue><spage>599</spage><epage>603</epage><pages>599-603</pages><issn>0300-5623</issn><issn>2194-7228</issn><eissn>1434-0879</eissn><eissn>2194-7236</eissn><abstract>The objective of the study is to compare the efficacy and safety of extracorporeal shock wave lithotripsy (ESWL) and mini-percutaneous nephrolithotomy (MPCNL) in treating renal stones sizing 15–25 mm in infants <3 years. Forty-six infants with renal stones sizing 15–30 mm were treated by either ESWL (22 renal units in 22 infants) using Dornier compact delta lithotripter or MPCNL (25 renal units in 24 infants) using 14F–18F renal access under general anesthesia. The operation time, stone-free rate, re-treatment rate, and complications between the two groups were compared with the χ
2
, Mann–Whitney
U
, and Student’s
t
tests. No significant differences in mean age and stone size were observed between the two groups. The 1- and 3-month postoperative stone-free rates were 84 and 96 % in MPCNL group and were 31.8 and 86.4 % in ESWL group. The re-treatment and complication rates were significantly higher in ESWL group than in MPCNL group (50 vs. 12 %,
P
= 0.004; 16.0 vs. 45.5 %,
P
= 0.028). The stone recurrence rate was similar between the two groups. No significant changes of serum creatinine (Cr) level and glomerular filtration rate were observed in both groups. In conclusion, MPCNL is an effective and feasible alternative monotherapy for large renal stones (15–25 mm) in infants, with a higher stone-free rate and a lower complication rate when compared with ESWL.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>22580634</pmid><doi>10.1007/s00240-012-0478-y</doi><tpages>5</tpages></addata></record> |
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| subjects | Child, Preschool Female Humans Infant Infant, Newborn Kidney Calculi - therapy Lithotripsy - adverse effects Lithotripsy - methods Male Medical Biochemistry Medicine Medicine & Public Health Nephrology Nephrostomy, Percutaneous - adverse effects Nephrostomy, Percutaneous - methods Original Paper Urology |
| title | Treatment of renal stones in infants: comparing extracorporeal shock wave lithotripsy and mini-percutaneous nephrolithotomy |
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