Incorporation of drug-resin complex to improve microsphere performance

The objective of present work was to incorporate drug-resin complex (DRC) to microspheres to achieve improved drug loading, less leakage, and extended zero order release. Ondensetron hydrochloride (ODH), a model drug was complexed with Indion 244, and incorporated to microspheres of hydroxypropyl me...

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Veröffentlicht in:	Asian journal of pharmaceutics 2012-01, Vol.6 (1), p.44
Hauptverfasser:	Jadhav, NamdeoR, Bhakare, HiteshR, Bhawale, BadrinathK
Format:	Artikel
Sprache:	eng
Schlagworte:	Aqueous solutions Chemical properties Controlled release Controlled release preparations Drug delivery systems Drugs Microspheres Pharmaceutical chemistry Pharmacology Polymers Properties R&D Research & development Resins Scanning electron microscopy
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