Role of indium-111 labelled platelet scintigraphy in the management of thrombocytopenic patients with malignant neoplasms
This study was done to investigate the role of indium-111 labelled platelet scintigraphy in the treatment of thrombocytopenia in patients with malignant neoplasms. The study involved 20 consecutive patients with thrombocytopenia associated with malignant neoplasms of hematological disorders and with...
Gespeichert in:
| Veröffentlicht in: | European journal of nuclear medicine 1998-03, Vol.25 (3), p.247-252 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 252 |
|---|---|
| container_issue | 3 |
| container_start_page | 247 |
| container_title | European journal of nuclear medicine |
| container_volume | 25 |
| creator | ORIUCHI, N KORKMAZ, M KIM, E. E DELPASSAND, E. S WONG, F WALLACE, S PODOLOFF, D. A |
| description | This study was done to investigate the role of indium-111 labelled platelet scintigraphy in the treatment of thrombocytopenia in patients with malignant neoplasms. The study involved 20 consecutive patients with thrombocytopenia associated with malignant neoplasms of hematological disorders and without evidence of underproduction of megakaryocytes due to chemotherapy or bone marrow infiltration by the malignancy. Splenic sequestration of platelets was evaluated by measuring splenic uptake of 111In-labelled platelets, and findings were correlated with the outcome of splenectomy and medication. Of the 20 patients, 13 had splenic sequestration of platelets. Seven of the 13 patients underwent splenectomy; six of these seven patients experienced a complete response. The other six patients received medication only and showed no response. Of the seven patients without splenic sequestration of platelets, five received medication, and four of them responded to it. 111In-labelled platelet scintigraphy has a role in selecting appropriate therapy and predicting its efficacy in patients with thrombocytopenia associated with malignant neoplasms. |
| doi_str_mv | 10.1007/s002590050224 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_1038764628</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2756329761</sourcerecordid><originalsourceid>FETCH-LOGICAL-c374t-ed11f00274ca959291ae59cc12965832a63569d28ded64c86f67c3b1302d3e6e3</originalsourceid><addsrcrecordid>eNpd0U2LFDEQBuAgyjq7evQoBJS9tVY-OznK4hcsCKLnJpOunsmSTtpOmmX-vVl2WNBTDu-TlyqKkDcMPjCA_mMB4MoCKOBcPiM7ppntejD2OdmBkNBpa_uX5LKUOwCQUqgLcmGVAaP6HTn9zBFpnmhIY9jmjjFGo9tjjDjSJbqKESstPqQaDqtbjqcmaT0inV1yB5wx1Yfv9bjmeZ_9qeYFU_B0cTW0rND7UI8Nx3BIrtmEudWWubwiLyYXC74-v1fk95fPv26-dbc_vn6_-XTbedHL2uHI2NRW7KV3VllumUNlvWfcamUEd1oobUduRhy19EZPuvdizwTwUaBGcUWuH3uXNf_ZsNRhDsW3BV0bZStDb43WEnSD7_6Dd3lbU5ttYCBMr6XmpqnuUfk1l7LiNCxrmN16amh4OMjwz0Gaf3tu3fYzjk_6fIGWvz_nrngXp9UlH8oT45wxDlz8BRTnksk</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1038764628</pqid></control><display><type>article</type><title>Role of indium-111 labelled platelet scintigraphy in the management of thrombocytopenic patients with malignant neoplasms</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>ORIUCHI, N ; KORKMAZ, M ; KIM, E. E ; DELPASSAND, E. S ; WONG, F ; WALLACE, S ; PODOLOFF, D. A</creator><creatorcontrib>ORIUCHI, N ; KORKMAZ, M ; KIM, E. E ; DELPASSAND, E. S ; WONG, F ; WALLACE, S ; PODOLOFF, D. A</creatorcontrib><description>This study was done to investigate the role of indium-111 labelled platelet scintigraphy in the treatment of thrombocytopenia in patients with malignant neoplasms. The study involved 20 consecutive patients with thrombocytopenia associated with malignant neoplasms of hematological disorders and without evidence of underproduction of megakaryocytes due to chemotherapy or bone marrow infiltration by the malignancy. Splenic sequestration of platelets was evaluated by measuring splenic uptake of 111In-labelled platelets, and findings were correlated with the outcome of splenectomy and medication. Of the 20 patients, 13 had splenic sequestration of platelets. Seven of the 13 patients underwent splenectomy; six of these seven patients experienced a complete response. The other six patients received medication only and showed no response. Of the seven patients without splenic sequestration of platelets, five received medication, and four of them responded to it. 111In-labelled platelet scintigraphy has a role in selecting appropriate therapy and predicting its efficacy in patients with thrombocytopenia associated with malignant neoplasms.</description><identifier>ISSN: 0340-6997</identifier><identifier>ISSN: 1619-7070</identifier><identifier>EISSN: 1619-7089</identifier><identifier>DOI: 10.1007/s002590050224</identifier><identifier>PMID: 9580857</identifier><identifier>CODEN: EJNMD9</identifier><language>eng</language><publisher>Berlin: Springer</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Autoantibodies - analysis ; Biological and medical sciences ; Blood Platelets - diagnostic imaging ; Blood Platelets - immunology ; Cancer ; Female ; Half-Life ; Hematologic and hematopoietic diseases ; Humans ; Indium Radioisotopes ; Male ; Medical research ; Medical sciences ; Middle Aged ; Mortality ; Neoplasms - complications ; Neoplasms - diagnostic imaging ; Other diseases. Hematologic involvement in other diseases ; Radionuclide Imaging ; Splenectomy ; Thrombocytopenia - complications ; Thrombocytopenia - diagnostic imaging ; Tumors</subject><ispartof>European journal of nuclear medicine, 1998-03, Vol.25 (3), p.247-252</ispartof><rights>1998 INIST-CNRS</rights><rights>Springer-Verlag Berlin Heidelberg 1998</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c374t-ed11f00274ca959291ae59cc12965832a63569d28ded64c86f67c3b1302d3e6e3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2211202$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9580857$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>ORIUCHI, N</creatorcontrib><creatorcontrib>KORKMAZ, M</creatorcontrib><creatorcontrib>KIM, E. E</creatorcontrib><creatorcontrib>DELPASSAND, E. S</creatorcontrib><creatorcontrib>WONG, F</creatorcontrib><creatorcontrib>WALLACE, S</creatorcontrib><creatorcontrib>PODOLOFF, D. A</creatorcontrib><title>Role of indium-111 labelled platelet scintigraphy in the management of thrombocytopenic patients with malignant neoplasms</title><title>European journal of nuclear medicine</title><addtitle>Eur J Nucl Med</addtitle><description>This study was done to investigate the role of indium-111 labelled platelet scintigraphy in the treatment of thrombocytopenia in patients with malignant neoplasms. The study involved 20 consecutive patients with thrombocytopenia associated with malignant neoplasms of hematological disorders and without evidence of underproduction of megakaryocytes due to chemotherapy or bone marrow infiltration by the malignancy. Splenic sequestration of platelets was evaluated by measuring splenic uptake of 111In-labelled platelets, and findings were correlated with the outcome of splenectomy and medication. Of the 20 patients, 13 had splenic sequestration of platelets. Seven of the 13 patients underwent splenectomy; six of these seven patients experienced a complete response. The other six patients received medication only and showed no response. Of the seven patients without splenic sequestration of platelets, five received medication, and four of them responded to it. 111In-labelled platelet scintigraphy has a role in selecting appropriate therapy and predicting its efficacy in patients with thrombocytopenia associated with malignant neoplasms.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Autoantibodies - analysis</subject><subject>Biological and medical sciences</subject><subject>Blood Platelets - diagnostic imaging</subject><subject>Blood Platelets - immunology</subject><subject>Cancer</subject><subject>Female</subject><subject>Half-Life</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Humans</subject><subject>Indium Radioisotopes</subject><subject>Male</subject><subject>Medical research</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Neoplasms - complications</subject><subject>Neoplasms - diagnostic imaging</subject><subject>Other diseases. Hematologic involvement in other diseases</subject><subject>Radionuclide Imaging</subject><subject>Splenectomy</subject><subject>Thrombocytopenia - complications</subject><subject>Thrombocytopenia - diagnostic imaging</subject><subject>Tumors</subject><issn>0340-6997</issn><issn>1619-7070</issn><issn>1619-7089</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNpd0U2LFDEQBuAgyjq7evQoBJS9tVY-OznK4hcsCKLnJpOunsmSTtpOmmX-vVl2WNBTDu-TlyqKkDcMPjCA_mMB4MoCKOBcPiM7ppntejD2OdmBkNBpa_uX5LKUOwCQUqgLcmGVAaP6HTn9zBFpnmhIY9jmjjFGo9tjjDjSJbqKESstPqQaDqtbjqcmaT0inV1yB5wx1Yfv9bjmeZ_9qeYFU_B0cTW0rND7UI8Nx3BIrtmEudWWubwiLyYXC74-v1fk95fPv26-dbc_vn6_-XTbedHL2uHI2NRW7KV3VllumUNlvWfcamUEd1oobUduRhy19EZPuvdizwTwUaBGcUWuH3uXNf_ZsNRhDsW3BV0bZStDb43WEnSD7_6Dd3lbU5ttYCBMr6XmpqnuUfk1l7LiNCxrmN16amh4OMjwz0Gaf3tu3fYzjk_6fIGWvz_nrngXp9UlH8oT45wxDlz8BRTnksk</recordid><startdate>19980301</startdate><enddate>19980301</enddate><creator>ORIUCHI, N</creator><creator>KORKMAZ, M</creator><creator>KIM, E. E</creator><creator>DELPASSAND, E. S</creator><creator>WONG, F</creator><creator>WALLACE, S</creator><creator>PODOLOFF, D. A</creator><general>Springer</general><general>Springer Nature B.V</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>19980301</creationdate><title>Role of indium-111 labelled platelet scintigraphy in the management of thrombocytopenic patients with malignant neoplasms</title><author>ORIUCHI, N ; KORKMAZ, M ; KIM, E. E ; DELPASSAND, E. S ; WONG, F ; WALLACE, S ; PODOLOFF, D. A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c374t-ed11f00274ca959291ae59cc12965832a63569d28ded64c86f67c3b1302d3e6e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Autoantibodies - analysis</topic><topic>Biological and medical sciences</topic><topic>Blood Platelets - diagnostic imaging</topic><topic>Blood Platelets - immunology</topic><topic>Cancer</topic><topic>Female</topic><topic>Half-Life</topic><topic>Hematologic and hematopoietic diseases</topic><topic>Humans</topic><topic>Indium Radioisotopes</topic><topic>Male</topic><topic>Medical research</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Neoplasms - complications</topic><topic>Neoplasms - diagnostic imaging</topic><topic>Other diseases. Hematologic involvement in other diseases</topic><topic>Radionuclide Imaging</topic><topic>Splenectomy</topic><topic>Thrombocytopenia - complications</topic><topic>Thrombocytopenia - diagnostic imaging</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>ORIUCHI, N</creatorcontrib><creatorcontrib>KORKMAZ, M</creatorcontrib><creatorcontrib>KIM, E. E</creatorcontrib><creatorcontrib>DELPASSAND, E. S</creatorcontrib><creatorcontrib>WONG, F</creatorcontrib><creatorcontrib>WALLACE, S</creatorcontrib><creatorcontrib>PODOLOFF, D. A</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of nuclear medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>ORIUCHI, N</au><au>KORKMAZ, M</au><au>KIM, E. E</au><au>DELPASSAND, E. S</au><au>WONG, F</au><au>WALLACE, S</au><au>PODOLOFF, D. A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Role of indium-111 labelled platelet scintigraphy in the management of thrombocytopenic patients with malignant neoplasms</atitle><jtitle>European journal of nuclear medicine</jtitle><addtitle>Eur J Nucl Med</addtitle><date>1998-03-01</date><risdate>1998</risdate><volume>25</volume><issue>3</issue><spage>247</spage><epage>252</epage><pages>247-252</pages><issn>0340-6997</issn><issn>1619-7070</issn><eissn>1619-7089</eissn><coden>EJNMD9</coden><abstract>This study was done to investigate the role of indium-111 labelled platelet scintigraphy in the treatment of thrombocytopenia in patients with malignant neoplasms. The study involved 20 consecutive patients with thrombocytopenia associated with malignant neoplasms of hematological disorders and without evidence of underproduction of megakaryocytes due to chemotherapy or bone marrow infiltration by the malignancy. Splenic sequestration of platelets was evaluated by measuring splenic uptake of 111In-labelled platelets, and findings were correlated with the outcome of splenectomy and medication. Of the 20 patients, 13 had splenic sequestration of platelets. Seven of the 13 patients underwent splenectomy; six of these seven patients experienced a complete response. The other six patients received medication only and showed no response. Of the seven patients without splenic sequestration of platelets, five received medication, and four of them responded to it. 111In-labelled platelet scintigraphy has a role in selecting appropriate therapy and predicting its efficacy in patients with thrombocytopenia associated with malignant neoplasms.</abstract><cop>Berlin</cop><pub>Springer</pub><pmid>9580857</pmid><doi>10.1007/s002590050224</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0340-6997 |
| ispartof | European journal of nuclear medicine, 1998-03, Vol.25 (3), p.247-252 |
| issn | 0340-6997 1619-7070 1619-7089 |
| language | eng |
| recordid | cdi_proquest_journals_1038764628 |
| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Adult Aged Aged, 80 and over Autoantibodies - analysis Biological and medical sciences Blood Platelets - diagnostic imaging Blood Platelets - immunology Cancer Female Half-Life Hematologic and hematopoietic diseases Humans Indium Radioisotopes Male Medical research Medical sciences Middle Aged Mortality Neoplasms - complications Neoplasms - diagnostic imaging Other diseases. Hematologic involvement in other diseases Radionuclide Imaging Splenectomy Thrombocytopenia - complications Thrombocytopenia - diagnostic imaging Tumors |
| title | Role of indium-111 labelled platelet scintigraphy in the management of thrombocytopenic patients with malignant neoplasms |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-29T20%3A02%3A41IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Role%20of%20indium-111%20labelled%20platelet%20scintigraphy%20in%20the%20management%20of%20thrombocytopenic%20patients%20with%20malignant%20neoplasms&rft.jtitle=European%20journal%20of%20nuclear%20medicine&rft.au=ORIUCHI,%20N&rft.date=1998-03-01&rft.volume=25&rft.issue=3&rft.spage=247&rft.epage=252&rft.pages=247-252&rft.issn=0340-6997&rft.eissn=1619-7089&rft.coden=EJNMD9&rft_id=info:doi/10.1007/s002590050224&rft_dat=%3Cproquest_cross%3E2756329761%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1038764628&rft_id=info:pmid/9580857&rfr_iscdi=true |