A review of Candida species causing blood stream infection
The incidence of candidemia has been on a rise worldwide. The epidemiology of invasive fungal infections in general and of candidemia in particular has changed in the past three decades because of a variety of factors like the AIDS epidemic, increased number of patients receiving immunosuppressive t...
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| Veröffentlicht in: | Indian journal of medical microbiology 2012-07, Vol.30 (3), p.270-278 |
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| creator | Giri, S Kindo, AJ |
| description | The incidence of candidemia has been on a rise worldwide. The epidemiology of invasive fungal infections in general and of candidemia in particular has changed in the past three decades because of a variety of factors like the AIDS epidemic, increased number of patients receiving immunosuppressive therapy for transplantation and the increasing use of antimicrobials in the hospital setups and even in the community. The important risk factors for candidemia include use of broad-spectrum antimicrobials, cancer chemotherapy, mucosal colonization by Candida species, indwelling vascular catheters like central venous catheters, etc. More than 90% of the invasive infections due to Candida species are attributed to five species—Candida albicans, Candida glabrata, Candida parapsilosis, Candida tropicalis and Candida krusei. However, the list of new species of Candida isolated from clinical specimens continues to grow every year. Early diagnosis and proper treatment is the key for management of candidemia cases. |
| doi_str_mv | 10.4103/0255-0857.99484 |
| format | Article |
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The epidemiology of invasive fungal infections in general and of candidemia in particular has changed in the past three decades because of a variety of factors like the AIDS epidemic, increased number of patients receiving immunosuppressive therapy for transplantation and the increasing use of antimicrobials in the hospital setups and even in the community. The important risk factors for candidemia include use of broad-spectrum antimicrobials, cancer chemotherapy, mucosal colonization by Candida species, indwelling vascular catheters like central venous catheters, etc. More than 90% of the invasive infections due to Candida species are attributed to five species—Candida albicans, Candida glabrata, Candida parapsilosis, Candida tropicalis and Candida krusei. However, the list of new species of Candida isolated from clinical specimens continues to grow every year. 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The epidemiology of invasive fungal infections in general and of candidemia in particular has changed in the past three decades because of a variety of factors like the AIDS epidemic, increased number of patients receiving immunosuppressive therapy for transplantation and the increasing use of antimicrobials in the hospital setups and even in the community. The important risk factors for candidemia include use of broad-spectrum antimicrobials, cancer chemotherapy, mucosal colonization by Candida species, indwelling vascular catheters like central venous catheters, etc. More than 90% of the invasive infections due to Candida species are attributed to five species—Candida albicans, Candida glabrata, Candida parapsilosis, Candida tropicalis and Candida krusei. However, the list of new species of Candida isolated from clinical specimens continues to grow every year. Early diagnosis and proper treatment is the key for management of candidemia cases.</description><subject>Antifungal Agents - therapeutic use</subject><subject>Antifungals</subject><subject>Cancer</subject><subject>Candida - classification</subject><subject>Candida - isolation & purification</subject><subject>candidemia</subject><subject>Candidemia - epidemiology</subject><subject>Candidemia - microbiology</subject><subject>Catheters</subject><subject>Early Diagnosis</subject><subject>echinocandins</subject><subject>Epidemiology</subject><subject>Humans</subject><subject>immunocompromised</subject><subject>Immunocompromised Host</subject><subject>Infections</subject><subject>Mortality</subject><subject>Prevalence</subject><issn>0255-0857</issn><issn>1998-3646</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp1kMtLAzEQh4MotlbP3iTgedtkk33EWym-oOBFzyGPiaS0m5rsKv73prb25mkY5pvfMB9C15RMOSVsRsqqKkhbNVMheMtP0JgK0Ras5vUpGh-nI3SR0orkngt-jkZl2bYVFXSM7uY4wqeHLxwcXqjOeqtw2oLxkLBRQ_LdO9brECxOfQS1wb5zYHofukt05tQ6wdWhTtDbw_3r4qlYvjw-L-bLwvC27AtjwGmqbWuNIFS5WmmtaUMoESWjrGK0cZQ1wpQNKOuAOlYTQ4TLmCstsAm63eduY_gYIPVyFYbY5ZMyK2BVXXMhMjXbUyaGlCI4uY1-o-J3huTOldzZkDsb8tdV3rg55A56A_bI_8nJgNgDkL_LjqJMWUtnwPqYFUgb_L_hP6FSdgw</recordid><startdate>20120701</startdate><enddate>20120701</enddate><creator>Giri, S</creator><creator>Kindo, AJ</creator><general>Elsevier B.V</general><general>Elsevier Limited</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7T7</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7N</scope><scope>MBDVC</scope><scope>P64</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope></search><sort><creationdate>20120701</creationdate><title>A review of Candida species causing blood stream infection</title><author>Giri, S ; 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The epidemiology of invasive fungal infections in general and of candidemia in particular has changed in the past three decades because of a variety of factors like the AIDS epidemic, increased number of patients receiving immunosuppressive therapy for transplantation and the increasing use of antimicrobials in the hospital setups and even in the community. The important risk factors for candidemia include use of broad-spectrum antimicrobials, cancer chemotherapy, mucosal colonization by Candida species, indwelling vascular catheters like central venous catheters, etc. More than 90% of the invasive infections due to Candida species are attributed to five species—Candida albicans, Candida glabrata, Candida parapsilosis, Candida tropicalis and Candida krusei. However, the list of new species of Candida isolated from clinical specimens continues to grow every year. Early diagnosis and proper treatment is the key for management of candidemia cases.</abstract><cop>India</cop><pub>Elsevier B.V</pub><pmid>22885191</pmid><doi>10.4103/0255-0857.99484</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Indian journal of medical microbiology, 2012-07, Vol.30 (3), p.270-278 |
| issn | 0255-0857 1998-3646 |
| language | eng |
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| source | MEDLINE; Bioline International; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Antifungal Agents - therapeutic use Antifungals Cancer Candida - classification Candida - isolation & purification candidemia Candidemia - epidemiology Candidemia - microbiology Catheters Early Diagnosis echinocandins Epidemiology Humans immunocompromised Immunocompromised Host Infections Mortality Prevalence |
| title | A review of Candida species causing blood stream infection |
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