Pirfenidone inhibits TGF-[beta]1-induced over-expression of collagen type I and heat shock protein 47 in A549 cells

Background Pirfenidone is a novel anti-fibrotic and anti-inflammatory agent that inhibits the progression of fibrosis in animal models and in patients with idiopathic pulmonary fibrosis (IPF). We previously showed that pirfenidone inhibits the over-expression of collagen type I and of heat shock pro...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	BMC pulmonary medicine 2012-06, Vol.12
Hauptverfasser:	Hisatomi, Keiko, Mukae, Hiroshi, Sakamoto, Noriho, Ishimatsu, Yuji, Kakugawa, Tomoyuki, Hara, Shintaro, Fujita, Hanako, Nakamichi, Seiko, Oku, Hisashi, Urata, Yoshishige, Kubota, Hiroshi, Nagata, Kazuhiro, Kohno, Shigeru
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Anti-inflammatory drugs Bone morphogenetic proteins Collagen Cytochemistry Fibronectins Health aspects Heat shock proteins Hospitals Lungs Medical research Medicine Pathogenesis Physiological aspects Proteins Pulmonology RNA Rodents Stem cells Transforming growth factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!