Glucose regulates LXR[alpha] subcellular localization and function in rat pancreatic [beta]-cells

Liver X receptors (LXRs) are members of the nuclear receptor superfamily, which have been implicated in lipid homeostasis and more recently in glucose metabolism. Here, we show that glucose does not change LXRalpha protein level, but affects its localization in pancreatic beta-cells. LXRalpha is fou...

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Veröffentlicht in:Cell research 2006-07, Vol.16 (7), p.661
Hauptverfasser: Helleboid-chapman, Audrey, Helleboid, Stéphane, Jakel, Heidelinde, Timmerman, Catherine, Sergheraert, Christian, Pattou, François, Fruchart-najib, Jamila, Fruchart, Jean-charles
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Sprache:eng
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