Dosimetric analysis of chimeric monoclonal antibody cMOv18 IgG in ovarian carcinoma patients after intraperitoneal and intravenous administration

In this study the potential of intraperitoneal (i.p.) and intravenous (i.v.) administration of chimeric iodine-131-labelled MOv18 IgG for radioimmunotherapy was determined. The dosimetry associated with both routes of administration of cMOv18 IgG was studied in patients. Eight patients suspected of...

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Veröffentlicht in:	European journal of nuclear medicine 1998-11, Vol.25 (11), p.1552-1561
Hauptverfasser:	BUIJS, W. C. A. M, TIBBEN, J. G, BOERMAN, O. C, MOLTHOFF, C. F. M, MASSUGER, L. F. A. G, KOENDERS, E. B, SCHIJF, C. P. T, SIEGEL, J. A, CORSTENS, F. H. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Antibodies, Monoclonal - administration & dosage Antibodies, Monoclonal - pharmacokinetics Ascitic Fluid - metabolism Biological and medical sciences Bone Marrow - diagnostic imaging Female Genital system. Mammary gland Humans Immunoglobulin G - administration & dosage Injections, Intraperitoneal Injections, Intravenous Medical sciences Middle Aged Ovarian Neoplasms - diagnostic imaging Ovarian Neoplasms - metabolism Radiometry Radionuclide Imaging Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Recombinant Fusion Proteins - administration & dosage Recombinant Fusion Proteins - pharmacokinetics Tissue Distribution
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