Loss of heterozygosity of the retinoblastoma gene in liver cirrhosis accompanying hepatocellular carcinoma

Carcinogenesis is a multistep process. Most hepatocellular carcinoma (HCC) is preceded by liver cirrhosis, but the genetic changes involved in cirrhosis are not known well. The present study was conducted to evaluate aberration of the retinoblastoma (RB) gene in HCC and adjacent non-tumorous liver u...

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Veröffentlicht in:	Journal of cancer research and clinical oncology 1997-12, Vol.123 (9), p.489-495
Hauptverfasser:	ASHIDA, K, KISHIMOTO, Y, NAKAMOTO, K, WADA, K, SHIOTA, G, HIROOKA, Y, KAMISAKI, Y, ITOH, T, KAWASAKI, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences DNA, Neoplasm - genetics Female Gastroenterology. Liver. Pancreas. Abdomen Genes, Retinoblastoma Hepatitis, Chronic - genetics Humans Liver Cirrhosis - genetics Liver Neoplasms - genetics Liver. Biliary tract. Portal circulation. Exocrine pancreas Loss of Heterozygosity Male Medical sciences Microsatellite Repeats Middle Aged Tumors
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