Near-Infrared Image-Guided Delivery and Controlled Release Using Optimized Thermosensitive Liposomes

ABSTRACT Purpose To engineer optimized near-infrared (NIR) active thermosensitive liposomes to potentially achieve image-guided delivery of chemotherapeutic agents. Methods Thermosensitive liposomes were surface-coated with either polyethylene glycol or dextran. Differential scanning calorimetry and...

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Veröffentlicht in:	Pharmaceutical research 2012-08, Vol.29 (8), p.2092-2103
Hauptverfasser:	Turner, David C., Moshkelani, Delaram, Shemesh, Colby S., Luc, David, Zhang, Hailing
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry Biomedical and Life Sciences Biomedical Engineering and Bioengineering Biomedicine Cell Line Coloring Agents - administration & dosage Coloring Agents - pharmacokinetics Delayed-Action Preparations - chemistry Delayed-Action Preparations - pharmacokinetics Dextrans - chemistry Differential scanning calorimetry Drug delivery systems Indocyanine Green - administration & dosage Indocyanine Green - pharmacokinetics Lipids Liposomes - chemistry Liposomes - pharmacokinetics Macrophages - cytology Medical Law Mice Mice, Inbred BALB C Neoplasms - diagnosis Phagocytosis Pharmaceutical sciences Pharmacology/Toxicology Pharmacy Polyethylene Glycols - chemistry Research Paper Surface Properties Temperature Tissue Distribution
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