A current viewpoint on structure and evolution of collagens. I. Fibrillar collagens

This review summarizes current data of structure of the most representative group of superfamily of collagens—fibrillar collagens. The attention is focused on structural organization of individual domains and their functional role in the hierarchical stacking of collagen α-chains. There are presente...

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Veröffentlicht in:Journal of evolutionary biochemistry and physiology 2012-03, Vol.48 (2), p.127-139
Hauptverfasser: Ivanova, V. P., Krivchenko, A. I.
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creator Ivanova, V. P.
Krivchenko, A. I.
description This review summarizes current data of structure of the most representative group of superfamily of collagens—fibrillar collagens. The attention is focused on structural organization of individual domains and their functional role in the hierarchical stacking of collagen α-chains. There are presented characteristics of the main stages of biosynthesis and the supramolecular processing of fibrillar collagens. Also considered are some aspects of evolution of fibrillar collagens. The role of duplication of genome and genes, intergene combination, and translocation of exons in evolution of collagen genes is discussed.
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subjects Animal Physiology
Biochemistry
Biomedical and Life Sciences
Collagen
Evolutionary Biology
Genomics
Life Sciences
Molecular biology
Reviews
title A current viewpoint on structure and evolution of collagens. I. Fibrillar collagens
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