Simple and Accurate In Vitro Method for Predicting Serum Protein Binding of HIV Integrase Strand Transfer Inhibitors

This chapter contains sections titled: Introduction Identification of Early Leads in Bristol‐Myers Squibb (BMS) Discovery Program Evaluating Protein Binding Effect on Integrase Inhibitors Development of In Vitro Displacement Assay for Protein Binding Estimations Conclusion Experimental Methods Ackno...

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Hauptverfasser:	Dicker, Ira B, Walker, Michael A, Lin, Zeyu, Terry, Brian, Pajor, Lori, Zheng, Ming, Naidu, B. Narasimhulu, Banville, Jacques, Meanwell, Nicholas A, Krystal, Mark
Format:	Buchkapitel
Sprache:	eng
Schlagworte:	CHEMISTRY HIV integrase inhibitor serum protein binding in vitro displacement assay protein binding effects
Online-Zugang:	Volltext
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