Hindering auxiliary anchors are potent modulators of peptide binding and selection by I-Ak class II molecules

Selection of particular antigen-derived peptides by class II MHC molecules determines the population of complexes represented on the antigen-presenting cell surface and available for T cell receptor engagement. This discriminating selection process results from unique interactions between the spectr...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2000-10, Vol.97 (21), p.11460-11465
Hauptverfasser:	Latek, R R, Petzold, S J, Unanue, E R
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Antigen-Antibody Reactions Biochemistry Biological Sciences Cell Line Histocompatibility Antigens Class II - immunology Humans Hybridomas - immunology Immunodominant Epitopes - immunology Immunology Molecular Sequence Data Peptides
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