Gene Expression, Synthesis, and Secretion of Interleukin 18 and Interleukin 1β Are Differentially Regulated in Human Blood Mononuclear Cells and Mouse Spleen Cells

Interleukin (IL)-18, formerly called interferon γ (IFN-γ)inducing factor, is biologically and structurally related to IL-1β . A comparison of gene expression, synthesis, and processing of IL-18 with that of IL-1β was made in human peripheral blood mononuclear cells (PBMCs) and in human whole blood....

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1999-03, Vol.96 (5), p.2256-2261
Hauptverfasser:	Puren, Adrian J., Fantuzzi, Giamila, Dinarello, Charles A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Sciences Blood Blood donation Cytokines Gene expression Ice Messenger RNA Mice Protein precursors Secretion Spleen cells
Online-Zugang:	Volltext
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