Development of gene-switch transgenic mice that inducibly express transforming growth factor β1 in the epidermis

Previous attempts to establish transgenic mouse models to study the functions of transforming growth factor β1 (TGFβ1) in the skin revealed controversial roles for TGFβ1 in epidermal growth (inhibition vs. stimulation) and resulted in neonatal lethality in one instance. To establish a viable transge...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 1999-07, Vol.96 (15), p.8483-8488
Hauptverfasser: Wang, Xiao-Jing, Liefer, Kristin M., Tsai, Sophia, O’Malley, Bert W., Roop, Dennis R.
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Sprache:eng
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