Natural Trans-Splicing in Carnitine Octanoyltransferase Pre-MRNAs in Rat Liver

Carnitine octanoyltransferase (COT) transports medium-chain fatty acids through the peroxisome. During isolation of a COT clone from a rat liver library, a cDNA in which exon 2 was repeated, was characterized. Reverse transcription-PCR amplifications of total RNAs from rat liver showed a three-band...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1998-10, Vol.95 (21), p.12185-12190
Hauptverfasser:	Caudevilla, Concha, Serra, Dolors, Miliar, Angel, Codony, Carles, Asins, Guillermina, Bach, Montserrat, Hegardt, Fausto G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Biological Sciences Carnitine Acyltransferases - genetics Cloning, Molecular Complementary DNA Cots DNA Primers DNA, Complementary Enzymes Exons Humans Introns Liver Liver - enzymology Messenger RNA Molecular Sequence Data Polymerase chain reaction Proteins Rats Reverse transcriptase polymerase chain reaction Ribonucleic acid RNA RNA Precursors - genetics RNA, Messenger - genetics Rodents Trans splicing
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