Nerve Growth Factor Rapidly Suppresses Basal, NMDA-Evoked, and AMPA-Evoked Nitric Oxide Synthase Activity in Rat Hippocampus in vivo

In adult forebrain, nerve growth factor (NGF) influences neuronal maintenance and axon sprouting and is neuroprotective in several injury models through mechanisms that are incompletely understood. Most NGF signaling is thought to occur after internalization and retrograde transport of trkA receptor...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1998-09, Vol.95 (18), p.10926-10931
Hauptverfasser:	Lam, H. H. D., Bhardwaj, A., O'Connell, M. T., Hanley, D. F., Traystman, R. J., Sofroniew, M. V.
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid - antagonists & inhibitors alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid - metabolism Animals Biological Sciences Brain Cells Cellular immunity Central nervous system Cholinergics Dialysis Excitatory Amino Acid Antagonists - pharmacology Forebrain Gases Hippocampus Hippocampus - drug effects Hippocampus - enzymology Microdialysis N-Methylaspartate - antagonists & inhibitors N-Methylaspartate - physiology Nerve Growth Factors - pharmacology Neurology Neurons Neuroscience Nitric Oxide Synthase - metabolism Rats Receptors Receptors, Glutamate - drug effects Receptors, Glutamate - physiology Recombinant Proteins - pharmacology Rodents
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