Visualizing the Dynamics of T Cell Activation: Intracellular Adhesion Molecule 1 Migrates Rapidly to the T Cell/B Cell Interface and Acts to Sustain Calcium Levels

T cell recognition typically involves both the engagement of a specific T cell receptor with a peptide/major histocompatibility complex (MHC) and a number of accessory interactions. One of the most important interactions is between the integrin lymphocyte function-associated antigen 1 (LFA-1) on the...

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