Alloantibodies can Discriminate Class I Major Histocompatibility Complex Molecules Associated with Various Endogenous Peptides

Molecules encoded by a single major histocompatibility complex class I gene can associate with any one of a large number of peptide ligands. T-cell receptors have the capacity to discriminate among these peptide-class I complexes and in many cases bind only a single peptide-class I complex with suff...

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