The Drosophila stubble-stubbloid gene encodes an apparent transmembrane serine protease required for epithelial morphogenesis

The Stubble-stubbloid (Sb-sbd) gene is required for hormone-dependent epithelial morphogenesis of imaginal discs of Drosophila, including the formation of bristles, legs, and wings. The gene has been cloned by using Sb-sbd-associated DNA lesions in a 20-kilobase (kb) region of a 263-kb genomic walk....

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1993-06, Vol.90 (11), p.4937-4941
Hauptverfasser:	Appel, L.F, Prout, M, Abu-Shumays, R, Hammonds, A, Garbe, J.C, Fristrom, D, Fristrom, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Base Sequence Biochemistry. Physiology. Immunology Biological and medical sciences Blotting, Northern Cell Membrane - enzymology CERDA (PELO) Chromosome Walking CITOPLASMA Cloning, Molecular CODE GENETIQUE CODIGO GENETICO Complementary DNA CYTOPLASME Disulfides DNA - genetics DNA - isolation & purification DROSOPHILA Drosophila melanogaster - embryology Drosophila melanogaster - genetics Drosophila melanogaster - growth & development Drosophila Proteins Embryo, Nonmammalian EPITELIO Epithelial Cells EPITHELIUM ESTEROIDES EXPRESION GENICA EXPRESSION DES GENES Fundamental and applied biological sciences. Psychology Genes Genes, Dominant Genes, Recessive Genetic mutation Genomics HORMONAS DE LA MUDA HORMONE DE MUE Imaginal discs Insecta Insects Invertebrates Larva Legs Membrane Proteins - genetics Membrane Proteins - metabolism Molecular Sequence Data MORFOGENESIS MORPHOGENESE Morphogenesis Morphogenesis - genetics Physical growth Physiology. Development PROTEASAS PROTEASE Protein Sorting Signals - genetics Proteins Pupa RNA - genetics RNA - isolation & purification SECUENCIA NUCLEICA Sequence Homology, Amino Acid SEQUENCE NUCLEIQUE SERINA SERINE Serine Endopeptidases - genetics Serine Endopeptidases - metabolism SOIES STEROIDE Transcription, Genetic
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