Distinct Combinations of NF-κB Subunits Determine the Specificity of Transcriptional Activation

The nuclear factor that binds to the κ light-chain enhancer of B cells (NF-κ B) is a transcription factor that regulates the expression of a variety of cellular and viral genes. NF-κ B is composed of distinct subunits, and at least four independent genes (p105, p100, p65, and c-rel) have been isolat...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1992-03, Vol.89 (5), p.1529-1533
Hauptverfasser:	Perkins, Neil D., Schmid, Roland M., Duckett, Colin S., Leung, Kwanyee, Rice, Nancy R., Nabel, Gary J.
Format:	Artikel
Sprache:	eng
Schlagworte:	B lymphocytes Base Sequence Biological and medical sciences Complementary DNA DNA DNA-Binding Proteins - physiology Enhancer Elements, Genetic Fundamental and applied biological sciences. Psychology Gene Expression Regulation Genes HIV Macromolecular Substances Molecular and cellular biology Molecular genetics Molecular Sequence Data NF-kappa B - physiology Plasmids Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins c-rel Regulatory Sequences, Nucleic Acid T lymphocytes Transactivation Transcription, Genetic Transcription. Transcription factor. Splicing. Rna processing Transcriptional Activation Transfection
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