Hormonal Regulation of the Thyrotropin β-Subunit Gene by Phosphorylation of the Pituitary-Specific Transcription Factor Pit-1

The pituitary-specific transcription factor Pit-1 is a cell-specific activator of prolactin and growth hormone gene transcription in the anterior pituitary. Pit-1 has also been shown to mediate both thyrotropin-releasing hormone (TRH) and cAMP stimulation of the prolactin and thyrotropin β-subunit (...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 1992-07, Vol.89 (13), p.5942-5945
Hauptverfasser: Steinfelder, Hans J., Radovick, Sally, Wondisford, Fredric E.
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Sprache:eng
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