Human Interferon γ Potently Induces the Synthesis of a 55-kDa Protein (γ2) Highly Homologous to Rabbit Peptide Chain Release Factor and Bovine Tryptophanyl-tRNA Synthetase

An interferon γ (IFN-γ)-inducible protein, γ2, was identified by two-dimensional gel electrophoresis of transformed human amnion (AMA) cell proteins. cDNA clones coding for this protein have been isolated and characterized as encoding a polypeptide with a predicted molecular weight of 53,165 and a p...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1991-12, Vol.88 (24), p.11520-11524
Hauptverfasser:	FLECKNER, J, RAMUSSEN, H. H, JUSTESEN, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Amino acids Amnion - drug effects Amnion - physiology Analysis of the immune response. Humoral and cellular immunity Animals Base Sequence Biological and medical sciences Blotting, Northern Cattle Cell lines Cells, Cultured Complementary DNA Electrophoresis Fundamental and applied biological sciences. Psychology Fundamental immunology Gels genes Humans Immunobiology Interferon-gamma - pharmacology Messenger RNA Microbiology Miscellaneous Molecular Sequence Data Nucleotides Oligodeoxyribonucleotides peptide chain release factor Peptide Termination Factors - genetics Peptide Termination Factors - metabolism Polymerase Chain Reaction Protein Biosynthesis Proteins Proteins - genetics Proteins - metabolism Rabbits Recombinant Proteins Regulatory factors and their cellular receptors RNA RNA, Messenger - analysis RNA, Messenger - genetics Sequence Homology, Nucleic Acid Transcription, Genetic tryptophan-tRNA ligase Tryptophan-tRNA Ligase - genetics Tryptophan-tRNA Ligase - metabolism Ungulates
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