Deactivation Kinetics of the Transduction Cascade of Vision

The response of the retinal rod cell to a dim flash lasts less than a second. This phototransduction is mediated by a guanine nucleotide-binding (G) protein cascade in which rhodopsin is the receptor, transducin is the G-protein, and the cGMP-specific phosphodiesterase (PDE) is the effector. Photoex...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1991-11, Vol.88 (21), p.9813-9817
Hauptverfasser:	Vuong, T. Minh, Chabre, Marc
Format:	Artikel
Sprache:	eng
Schlagworte:	3',5'-Cyclic-GMP Phosphodiesterases - metabolism 3',5'-cyclic-nucleotide phosphodiesterase Animals Biochemistry Biological and medical sciences Biophysics Calorimetry Cattle Cell physiology Equilibrium flow Fundamental and applied biological sciences. Psychology Guanosine Triphosphate - metabolism Heat Hydrolysis In Vitro Techniques Kinetics Molecular and cellular biology Nucleotides Photochemistry Photoexcitation Receptors Rod Cell Outer Segment - metabolism Signal reflection Thermodynamics transducin Transducin - metabolism Vision, Ocular Vision, photoreception
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