Chromosomal Location of Three Spectrin Genes: Relationship to the Inherited Hemolytic Anemias of Mouse and Man

Three genetic loci in the mouse affect the synthesis and assembly of the erythrocyte membrane skeleton. The spherocytosis and jaundiced loci affect the membrane skeletal protein known as spectrin. The normoblastosis locus affects the spectrin binding protein called ankyrin. We have obtained genetic...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1988-11, Vol.85 (21), p.8121-8125
Hauptverfasser:	Birkenmeier, Connie S., McFarland-Starr, Eleanor C., Barker, Jane E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Anemia, Hemolytic - genetics Animals Biological and medical sciences Brain Chemistry Cell membranes Chromosome Mapping Chromosomes Chromosomes, Human, Pair 1 Chromosomes, Human, Pair 12 Classical genetics, quantitative genetics, hybrids Erythrocyte membrane Fundamental and applied biological sciences. Psychology Genes Genetic Linkage Genetic loci Genetic mapping Genetic mutation Genetics of eukaryotes. Biological and molecular evolution Hemolytic anemia Human Humans Jaundice - genetics Mice Mice, Inbred Strains Spectrin - genetics Spherocytosis, Hereditary - genetics Vertebrata
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