Localization of Ca2+Release Channels with Ryanodine in Junctional Terminal Cisternae of Sarcoplasmic Reticulum of Fast Skeletal Muscle

The mechanism of Ca2+release from sarcoplasmic reticulum, which triggers contraction in skeletal muscle, remains the key unresolved problem in excitation-contraction coupling. Recently, we have described the isolation of purified fractions referable to terminal and longitudinal cisternae of sarcopla...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1985-11, Vol.82 (21), p.7256-7259
Hauptverfasser:	Fleischer, Sidney, Ogunbunmi, Eunice M., Dixon, Mark C., Eduard A. M. Fleer
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaloids - pharmacology Animals Biological and medical sciences Calcium Calcium - metabolism Cell membranes Cell physiology Fundamental and applied biological sciences. Psychology Ion Channels - analysis Ion Channels - drug effects Kinetics Loading rate Molecular and cellular biology Muscle contraction Muscle Contraction - drug effects Muscles Pharmacologic actions Pumps Rabbits Ruthenium Ruthenium Red - antagonists & inhibitors Ryanodine - pharmacology Sarcoplasmic reticulum Sarcoplasmic Reticulum - analysis Sarcoplasmic Reticulum - ultrastructure Skeletal muscle
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