Isolation and Characterization of Polyoma Virus Mutants able to Develop in Embryonal Carcinoma Cells

Embryonal carcinoma (EC) mouse cells have been shown to be resistant to infection by retroviruses and small oncogenic DNA viruses, including simian virus 40 and polyoma. When allowed to differentiate, in vitro or in vivo, EC cells become as susceptible to these viruses as differentiated mouse cell l...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1980-02, Vol.77 (2), p.1068-1072
Hauptverfasser:	Vasseur, Marc, Kress, Chantal, Montreau, Nicole, Blangy, Daniel
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Cell Line Cell lines Cellular differentiation DNA Restriction Enzymes DNA, Viral - genetics Embryonal carcinoma stem cells Embryonic stem cells Genomes Infections Multipotent stem cells Mutation Neoplasms, Experimental - microbiology Polyomavirus - genetics Stem cells Teratoma - microbiology Viral tumor antigens Virus Replication Viruses
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