Nicotinic Acetylcholine Receptor: Evidence for a Functionally Distinct Receptor on Human Lymphocytes

The presence of three distinct cholinergic receptors on human lymphocytes was suggested by the effects of carbamoylcholine on lymphocyte proliferation in vitro. The cells responded to both 0.1 nM and 1 μ M carbamoylcholine by increased proliferation which was blocked by the muscarinic antagonist atr...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1979-09, Vol.76 (9), p.4632-4635
Hauptverfasser:	Richman, David P., Barry G. W. Arnason
Format:	Artikel
Sprache:	eng
Schlagworte:	Atropine Carbachol - pharmacology Cell Division - drug effects Cell growth Cholinergics Dose-Response Relationship, Drug Humans Ligands Lymphocyte Activation - drug effects Lymphocytes Lymphocytes - cytology Lymphocytes - metabolism Muscarinic receptors Myasthenia gravis Myasthenia Gravis - immunology Nicotinic antagonists Nicotinic receptors Parasympatholytics - pharmacology Receptors Receptors, Cholinergic - metabolism Receptors, Nicotinic - metabolism
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