T Lymphocyte Response to H-2 Mutants: Cytotoxic Effectors are Ly-1+2

The lymphocyte differentiation (Ly) antigen phenotype of cytotoxic effector T cells specific for H-2 mutant alloantigens was determined. Cytotoxic effectors generated in primary mixed lymphocyte culture and specific for H-2Kbaand H-2Ddaalloantigens are sensitive to both anti-Ly-1 and anti-Ly-2 serum...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1979-07, Vol.76 (7), p.3455-3459
Hauptverfasser:	Wettstein, Peter J., Bailey, Donald W., Mobraaten, Larry E., Klein, Jan, Frelinger, Jeffrey A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Animals Antigens Cytolysis Cytotoxicity Cytotoxicity, Immunologic Genes, MHC Class II H-2 Antigens - genetics Isoantigens Isoantigens - genetics Lymphocyte Activation Lymphocyte Culture Test, Mixed Lymphocytes Mice Mixed lymphocyte culture test Mutation Phenotype Phenotypes Spleen cells T lymphocytes T-Lymphocytes - immunology
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