Insulin Receptor: Interaction with Nonreceptor Glycoprotein from Liver Cell Membranes

In crude receptor preparations (either particulate or soluble) of rat liver membranes, the insulin receptor exhibits complicated binding kinetics (two binding plateaus, half-saturated at approximately 60 pM and 700 pM insulin) and an apparent chromatographic heterogeneity, suggested by the presence...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1978-07, Vol.75 (7), p.3070-3074
Hauptverfasser:	Maturo, Joseph M., Hollenberg, Morley D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue - metabolism Animals Biological Sciences: Biochemistry Cell membranes Chromatography Elution Erythrocyte Membrane - metabolism Glycoproteins Glycoproteins - metabolism Insulin Insulin - metabolism Isotherms Kinetics Liver Liver - metabolism Male Membrane Proteins - metabolism P branes Rats Receptor, Insulin - metabolism Receptors Solubility
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