Estrogen-Directed Synthesis of Specific Prostaglandins in Uterus

Endogenous uterine prostaglandin levels were monitored in the cycling rat and prostaglandins of the F-type were found to rise at proestrus when estrogen levels have been shown to be maximal. Evidence that this is an estrogen-induced event is furnished by the finding that estradiol-17β caused a simil...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1975-04, Vol.72 (4), p.1420-1424
Hauptverfasser:	Ham, E. A., Cirillo, V. J., Zanetti, M. E., Kuehl, F. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetates Animals Castration Cyclic AMP - metabolism Cyclic GMP - metabolism Diestrus Estradiol - pharmacology Estrogens Estrogens - pharmacology Estrus Estrus cycle Female Hormonal regulation Indomethacin - pharmacology Microsomes Microsomes - metabolism Ovary - physiology Pregnancy Proestrus Progesterone - pharmacology Prostaglandin-Endoperoxide Synthases - metabolism Prostaglandins Prostaglandins - biosynthesis Prostaglandins F - biosynthesis Rats Time Factors Uterus Uterus - drug effects Uterus - metabolism
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