Evidence for Position-Effect Suppression of the Ribosomal RNA Cistrons in Drosophila melanogaster

Evidence for Position-Effect Suppression of the Ribosomal RNA Cistrons in Drosophila melanogaster

Unambiguous evidence is presented that two X-chromosome inversions produce lethality in X/O males because of position-effect suppression of genes in the basal heterochromatin. The data support the hypothesis that the ribosomal RNA cistrons are the genes suppressed. There is evidence for a region in...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 1971-10, Vol.68 (10), p.2472-2476
1. Verfasser: Baker, William K.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Biological Sciences: Genetics
Chromosome Aberrations
Chromosome Mapping
Chromosomes
Crosses, Genetic
Drosophila melanogaster
Female
Genes
Genetic Code
Genotype
Genotypes
Heterochromatin
Larvae
Male
Nucleolus organizer region
Phenotype
Recombination, Genetic
Ribosomal DNA
RNA, Ribosomal - biosynthesis
Sex Chromosomes
Viability
X chromosome
Y chromosome
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Beschreibung
Zusammenfassung:Unambiguous evidence is presented that two X-chromosome inversions produce lethality in X/O males because of position-effect suppression of genes in the basal heterochromatin. The data support the hypothesis that the ribosomal RNA cistrons are the genes suppressed. There is evidence for a region in the X basal heterochromatin that may act as a regulator of rDNA activity.
ISSN:0027-8424
1091-6490
DOI:10.1073/pnas.68.10.2472