The Chain Growth Rate of T4 Lysozyme in vitro
The average interval between attachment of a 30S ribosomal subunit to bacteriophage T4 lysozyme mRNA and the completion of synthesis of lysozyme protein has been measured in vitro. The measured completion times yield rates of polypeptide chain propagation of 1.6 and 3.0 amino acids per second at 25...
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| Veröffentlicht in: | Proceedings of the National Academy of Sciences - PNAS 1970-02, Vol.65 (2), p.388-394 |
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| container_title | Proceedings of the National Academy of Sciences - PNAS |
| container_volume | 65 |
| creator | Wilhelm, James M. Haselkorn, Robert |
| description | The average interval between attachment of a 30S ribosomal subunit to bacteriophage T4 lysozyme mRNA and the completion of synthesis of lysozyme protein has been measured in vitro. The measured completion times yield rates of polypeptide chain propagation of 1.6 and 3.0 amino acids per second at 25 degrees C and 31 degrees C, respectively. |
| doi_str_mv | 10.1073/pnas.65.2.388 |
| format | Article |
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The measured completion times yield rates of polypeptide chain propagation of 1.6 and 3.0 amino acids per second at 25 degrees C and 31 degrees C, respectively.</description><subject>Amino acids</subject><subject>Biochemistry</subject><subject>Biological Sciences: Biochemistry</subject><subject>Carbon Isotopes</subject><subject>Coliphages - cytology</subject><subject>Coliphages - enzymology</subject><subject>Cyclohexanecarboxylic Acids - pharmacology</subject><subject>Enzymes</subject><subject>Infections</subject><subject>Lysine - metabolism</subject><subject>Messenger RNA</subject><subject>Muramidase - biosynthesis</subject><subject>Peptides - metabolism</subject><subject>Polynucleotides - pharmacology</subject><subject>Protein synthesis</subject><subject>Radioactive decay</subject><subject>Ribosomes</subject><subject>Ribosomes - metabolism</subject><subject>RNA</subject><subject>RNA, Messenger - metabolism</subject><subject>RNA, Transfer - metabolism</subject><subject>Transfer RNA</subject><subject>Viral Proteins - biosynthesis</subject><issn>0027-8424</issn><issn>1091-6490</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1970</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kDFPwzAQRi0EKqUwsiCQssCWYDu24wwMqIKCVAkJldlyHZukSuJiJ4Xy60nVUGBhuuG97-70AXCKYIRgEl8va-kjRiMcxZzvgSGCKQoZSeE-GEKIk5ATTA7BkfcLCGFKORyAAcUsThI8BOEs18E4l0UdTJx9b_LgWTY6sCaYkWC69vZzXemgo6uicfYYHBhZen3SzxF4ub-bjR_C6dPkcXw7DVXMGA8zSliawAwyoiGSSmYKJwpRyhmnZs6VYkbSmOmMKi1pgnhGDEZYSgSpiWE8Ajfbvct2XulM6bpxshRLV1TSrYWVhfhL6iIXr3YlMMcpol3-qs87-9Zq34iq8EqXpay1bb3ghCScY9SJ4VZUznrvtNndQFBs6hWbegWjAouu3s6_-P3Yzu777Ph5zzexb_orfvkPFqYty0Z_NJ13tvUWvrHu50rKKI6_AEdllYc</recordid><startdate>19700201</startdate><enddate>19700201</enddate><creator>Wilhelm, James M.</creator><creator>Haselkorn, Robert</creator><general>National Academy of Sciences of the United States of America</general><general>National Acad Sciences</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19700201</creationdate><title>The Chain Growth Rate of T4 Lysozyme in vitro</title><author>Wilhelm, James M. ; Haselkorn, Robert</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3668-d546970d064e01acadc27c1558685fb8cc6fa536ed5cea5718d4f212aa105f303</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1970</creationdate><topic>Amino acids</topic><topic>Biochemistry</topic><topic>Biological Sciences: Biochemistry</topic><topic>Carbon Isotopes</topic><topic>Coliphages - cytology</topic><topic>Coliphages - enzymology</topic><topic>Cyclohexanecarboxylic Acids - pharmacology</topic><topic>Enzymes</topic><topic>Infections</topic><topic>Lysine - metabolism</topic><topic>Messenger RNA</topic><topic>Muramidase - biosynthesis</topic><topic>Peptides - metabolism</topic><topic>Polynucleotides - pharmacology</topic><topic>Protein synthesis</topic><topic>Radioactive decay</topic><topic>Ribosomes</topic><topic>Ribosomes - metabolism</topic><topic>RNA</topic><topic>RNA, Messenger - metabolism</topic><topic>RNA, Transfer - metabolism</topic><topic>Transfer RNA</topic><topic>Viral Proteins - biosynthesis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wilhelm, James M.</creatorcontrib><creatorcontrib>Haselkorn, Robert</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Proceedings of the National Academy of Sciences - PNAS</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wilhelm, James M.</au><au>Haselkorn, Robert</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Chain Growth Rate of T4 Lysozyme in vitro</atitle><jtitle>Proceedings of the National Academy of Sciences - PNAS</jtitle><addtitle>Proc Natl Acad Sci U S A</addtitle><date>1970-02-01</date><risdate>1970</risdate><volume>65</volume><issue>2</issue><spage>388</spage><epage>394</epage><pages>388-394</pages><issn>0027-8424</issn><eissn>1091-6490</eissn><abstract>The average interval between attachment of a 30S ribosomal subunit to bacteriophage T4 lysozyme mRNA and the completion of synthesis of lysozyme protein has been measured in vitro. 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| identifier | ISSN: 0027-8424 |
| ispartof | Proceedings of the National Academy of Sciences - PNAS, 1970-02, Vol.65 (2), p.388-394 |
| issn | 0027-8424 1091-6490 |
| language | eng |
| recordid | cdi_pnas_primary_65_2_388 |
| source | MEDLINE; Jstor Complete Legacy; PubMed Central; Alma/SFX Local Collection; Free Full-Text Journals in Chemistry |
| subjects | Amino acids Biochemistry Biological Sciences: Biochemistry Carbon Isotopes Coliphages - cytology Coliphages - enzymology Cyclohexanecarboxylic Acids - pharmacology Enzymes Infections Lysine - metabolism Messenger RNA Muramidase - biosynthesis Peptides - metabolism Polynucleotides - pharmacology Protein synthesis Radioactive decay Ribosomes Ribosomes - metabolism RNA RNA, Messenger - metabolism RNA, Transfer - metabolism Transfer RNA Viral Proteins - biosynthesis |
| title | The Chain Growth Rate of T4 Lysozyme in vitro |
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