Spatial structure of neuronal receptive field in awake monkey secondary visual cortex (V2)
Visual processing depends critically on the receptive field (RF) properties of visual neurons. However, comprehensive characterization of RFs beyond the primary visual cortex (V1) remains a challenge. Here we report fine RF structures in secondary visual cortex (V2) of awake macaque monkeys, identif...
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| Veröffentlicht in: | Proceedings of the National Academy of Sciences - PNAS 2016-02, Vol.113 (7), p.1913-1918 |
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| container_title | Proceedings of the National Academy of Sciences - PNAS |
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| creator | Liu, Lu She, Liang Chen, Ming Liu, Tianyi Lu, Haidong D. Dan, Yang Poo, Mu-ming |
| description | Visual processing depends critically on the receptive field (RF) properties of visual neurons. However, comprehensive characterization of RFs beyond the primary visual cortex (V1) remains a challenge. Here we report fine RF structures in secondary visual cortex (V2) of awake macaque monkeys, identified through a projection pursuit regression analysis of neuronal responses to natural images. We found that V2 RFs could be broadly classified as V1-like (typical Gabor-shaped subunits), ultralong (subunits with high aspect ratios), or complex-shaped (subunits with multiple oriented components). Furthermore, single-unit recordings from functional domains identified by intrinsic optical imaging showed that neurons with ultralong RFs were primarily localized within pale stripes, whereas neurons with complex-shaped RFs were more concentrated in thin stripes. Thus, by combining single-unit recording with optical imaging and a computational approach, we identified RF subunits underlying spatial feature selectivity of V2 neurons and demonstrated the functional organization of these RF properties. |
| doi_str_mv | 10.1073/pnas.1525505113 |
| format | Article |
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However, comprehensive characterization of RFs beyond the primary visual cortex (V1) remains a challenge. Here we report fine RF structures in secondary visual cortex (V2) of awake macaque monkeys, identified through a projection pursuit regression analysis of neuronal responses to natural images. We found that V2 RFs could be broadly classified as V1-like (typical Gabor-shaped subunits), ultralong (subunits with high aspect ratios), or complex-shaped (subunits with multiple oriented components). Furthermore, single-unit recordings from functional domains identified by intrinsic optical imaging showed that neurons with ultralong RFs were primarily localized within pale stripes, whereas neurons with complex-shaped RFs were more concentrated in thin stripes. 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| subjects | Animals Biological Sciences Brain Eyes & eyesight Macaca Macaca - physiology Models, Biological Monkeys & apes Neurons Neurons - physiology Regression analysis Visual Cortex - cytology Visual Cortex - physiology Wakefulness |
| title | Spatial structure of neuronal receptive field in awake monkey secondary visual cortex (V2) |
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