Key bioactive reaction products of the NO/H₂S interaction are S/N-hybrid species, polysulfides, and nitroxyl

Experimental evidence suggests that nitric oxide (NO) and hydrogen sulfide (H₂S) signaling pathways are intimately intertwined, with mutual attenuation or potentiation of biological responses in the cardiovascular system and elsewhere. The chemical basis of this interaction is elusive. Moreover, pol...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2015-08, Vol.112 (34), p.E4651-E4660
Hauptverfasser:	Cortese-Krott, Miriam M., Kuhnle, Gunter G. C., Dyson, Alex, Fernandez, Bernadette O., Grman, Marian, DuMond, Jenna F., Barrow, Mark P., McLeod, George, Nakagawa, Hidehiko, Ondrias, Karol, Nagy, Péter, King, S. Bruce, Saavedra, Joseph E., Keefer, Larry K., Singer, Mervyn, Kelm, Malte, Butler, Anthony R., Feelisch, Martin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Availability Biological Sciences Hydrogen Sulfide - metabolism Male Nitric Oxide - metabolism Nitrogen - metabolism Nitrogen Oxides - metabolism Physical Sciences PNAS Plus Rats, Wistar Sulfides - metabolism Sulfur - metabolism
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