glioma classification scheme based on coexpression modules of EGFR and PDGFRA

We hypothesized that key signaling pathways of glioma genesis might enable the molecular classification of gliomas. Gene coexpression modules around epidermal growth factor receptor (EGFR) (EM, 29 genes) or platelet derived growth factor receptor A (PDGFRA) (PM, 40 genes) in gliomas were identified....

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2014-03, Vol.111 (9), p.3538-3543
Hauptverfasser:	Sun, Yingyu, Zhang, Wei, Chen, Dongfeng, Lv, Yuhong, Zheng, Junxiong, Lilljebjörn, Henrik, Ran, Liang, Bao, Zhaoshi, Soneson, Charlotte, Sjögren, Hans Olov, Salford, Leif G., Ji, Jianguang, French, Pim J., Fioretos, Thoas, Jiang, Tao, Fan, Xiaolong
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Animals Astrocytes Basic Medicine Biological Sciences Cell and Molecular Biology Cell- och molekylärbiologi China Classification Cluster Analysis Datasets Epidermal growth factor Gene expression Gene Expression Profiling Gene Expression Regulation, Neoplastic - genetics Genes Genomes Genomics Glioblastoma Glioma Glioma - classification Glioma - genetics Humans Kaplan-Meier Estimate Medical and Health Sciences Medicin och hälsovetenskap Medicinska och farmaceutiska grundvetenskaper Mice Morphology Neural Stem Cells - metabolism Polymorphism, Single Nucleotide - genetics Prognosis Receptor, Epidermal Growth Factor - genetics Receptor, Epidermal Growth Factor - metabolism Receptor, Platelet-Derived Growth Factor alpha - genetics Receptor, Platelet-Derived Growth Factor alpha - metabolism Signal transduction Signal Transduction - genetics Signatures Stem cells Tumors
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