Tau pathology involves protein phosphatase 2A in Parkinsonism-dementia of Guam

Parkinsonism-dementia (PD) of Guam is a neurodegenerative disease with parkinsonism and early-onset Alzheimer-like dementia associated with neurofibrillary tangles composed of hyperphosphorylated microtubule-associated protein, tau. β- N -methylamino- l -alanine (BMAA) has been suspected of being in...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2014-01, Vol.111 (3), p.1144-1149
Hauptverfasser:	Arif, Mohammad, Kazim, Syed Faraz, Grundke-Iqbal, Inge, Garruto, Ralph M., Iqbal, Khalid
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Alzheimers disease Amyotrophic lateral sclerosis Amyotrophic Lateral Sclerosis - metabolism Animals Biological Sciences Brain Brain - enzymology Dementia Enzymes Experiments Female Gene Expression Regulation, Enzymologic Hippocampus - metabolism Humans Male Mice Mice, Inbred C57BL Middle Aged Neurodegenerative diseases Neurons Neurons - metabolism Neurotoxins Neurotoxins - metabolism Parkinson's disease Pathology Phosphatases Phosphorylation Protein Phosphatase 2 - metabolism Proteins Rats Rats, Wistar Receptor, Metabotropic Glutamate 5 - metabolism Receptors RNA, Messenger - metabolism Rodents src-Family Kinases - metabolism tau Proteins - metabolism Time Factors Tyrosine - chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!