Functioning of a metabolic flux sensor in Escherichia coli

Regulation of metabolic operation in response to extracellular cues is crucial for cells’ survival. Next to the canonical nutrient sensors, which measure the concentration of nutrients, recently intracellular “metabolic flux” was proposed as a novel impetus for metabolic regulation. According to thi...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2013-01, Vol.110 (3), p.1130-1135
Hauptverfasser:	Kochanowski, Karl, Volkmer, Benjamin, Gerosa, Luca, van Rijsewijk, Bart R. Haverkorn, Schmidt, Alexander, Heinemann, Matthias
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biological Sciences Carbon Cellular metabolism E coli Enzymes Escherichia coli Escherichia coli K12 - genetics Escherichia coli K12 - metabolism Feedback, Physiological Fructose-Bisphosphatase - metabolism Genes, Bacterial Glycolysis Kinases Kinetics Metabolic Networks and Pathways Metabolism Metabolites Models, Biological nutrients Plasmids pyruvate kinase Pyruvate Kinase - genetics Pyruvate Kinase - metabolism Sensors Signal transduction Transcription factors Transcription, Genetic
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